CHUCK NORRIS AGAINST QUANTUM DOTS
Gadolinium carbon quantum dots as MRI contrast agents
https://www.cbsnews.com/news/chuck-norris-gena-norris-lawsuit-medical-companies-mri-contrast-agent/
Actor Chuck Norris and his wife, Gena, are suing 11 medical companies after they say she was poisoned by a drug used during a routine MRI scan. The drug is a contrast agent, which enhances MRI images and helps with diagnosis.
The companies that make contrast agents say they are safe and have been used to aid in the treatment of millions of patients, but the Norrises aren't the only ones complaining about the side effects and Gena hopes their lawsuit brings more attention to the issue, reports CBS News correspondent Anna Werner.
"I couldn't think any more, any type of cognition, being able to articulate, my memory, I had muscle wasting," Gena said.
"Nothing's going on here, she's dying, she's dying right in front of me here at this hospital," Chuck said.
MRI's help doctors diagnose disease by taking pictures inside the body. Sometimes doctors inject a drug called a contrast agent during the procedure, to get sharper images.
The Norrises blame a gadolinium-based agent for her health problems saying in their lawsuit that she developed gadolinium deposition disease, with symptoms including
burning pain, violent shaking and confusion, along with "kidney damage."
"We have clients
who have been misdiagnosed with
Lyme disease, ALS,
and then they've eventually ruled all those things out and the culprit remaining is the gadolinium,"
said the couple's attorney Todd Walburg.
The FDA started looking at this in 2015 and earlier this year said it had not identified any harmful effects from gadolinium that stayed in the brain.
Gadolinium-based Contrast Media Market 2023 Size Share and Growth 2023-2030 - Benzinga
https://www.sciencedirect.com/science/article/abs/pii/S0142961210013116 Fluorescence-enhanced gadolinium-doped zinc oxide quantum dots for magnetic resonance and fluorescence imaging - ScienceDirect
Lipid-based nanoparticles, such as liposomes or micelles, have been used extensively in recent decades as drug carrier vehicles. A relatively new and promising application of lipidic nanoparticles is their use as multimodal MR contrast agents. Lipids are amphiphilic molecules with both a hydrophobic and a hydrophilic part, which spontaneously assemble into aggregates in an aqueous environment. In these aggregates, the amphiphiles are arranged such that the hydrophobic parts cluster together and the hydrophilic parts face the water. In the low concentration regime, a wide variety of structures can be formed, ranging from spherical micelles to disks or liposomes. Furthermore, a monolayer of lipids can serve as a shell to enclose a hydrophobic core. Hydrophobic iron oxide particles, quantum dots or perfluorocarbon emulsions can be solubilized using this approach. MR-detectable and fluorescent amphiphilic molecules can easily be incorporated in lipidic nanoparticles. Furthermore, targeting ligands can be conjugated to lipidic particles by incorporating lipids with a functional moiety to allow a specific interaction with molecular markers and to achieve accumulation of the particles at disease sites. In this review, an overview of different lipidic nanoparticles for use in MRI is given, with the main emphasis on Gd-based contrast agents. The mechanisms of particle formation, conjugation strategies and applications in the field of contrast-enhanced, cellular and molecular MRI are discussed.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7221622/ A Novel Biocompatible Titanium–Gadolinium Quantum Dot as a Bacterial Detecting Agent with High Antibacterial Activity - PMC (nih.gov)
Nanoparticles, nowadays, are the focus of medical sciences with various applications like drug delivery,
tracking,
and alternatives to antibiotics such as nanomedicine [18,19,20].
However, nanoparticles also have adverse effects toward human health.
Nanoparticles exert various kinds of toxicity, they can be cancerous, affect our immune system, liver, spleen, can generate cellular ROS, damage our DNA, or they can also affect our metabolism through blocking or disrupting various enzymatic pathways [21,22].
https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/epdf/10.1002/jat.4180 Toxicity of quantum dots on target organs and immune system (wiley.com)
The toxicity of QDs in the environment and biological systems has caused widespread concern in the nanosphere, but their immune toxicity and their impact on the immune system are still relatively unknown. At present, the research on the toxicity of QDs is mainly focused on in vitro models, but few have systematically evaluated their adverse effects on target organs. Animal studies have shown that QDs can be accumulated in various organs due to their main exposure routes, thereby posing a potential threat to major organs. This review briefly describes general characteristics and the wide medical applications of QDs and focuses on the adverse effects of QDs on major target organs, such as liver, lung, kidney, brain, and spleen, after acute and chronic exposure. QDs mainly cause changes in the corresponding indicators of target organs, such as
oxidative damage, and in severe cases cause hyperemia, tissue necrosis, and even death.
In addition to causing direct damage to target organs, QDs can also cause a large number of immune cells to accumulate and cause inflammatory reactions when causing damage to other major organs.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311601/ Revisiting the cytotoxicity of quantum dots: an in-depth overview - PMC (nih.gov)
Mechanisms of QD cytotoxicity
Although QDs have received much attention and have entered into preclinical use, one key unresolved issue is their potential toxicity. It has been suggested that QD toxicity can be rationalized based on their physicochemical properties, such as core-shell materials, size, surface charge, ligands nature, and interaction with other present molecules in biological media (Oh et al. 2016).
In other words, their toxicity may be due to either some inherent chemical feature or their nanoscale properties.
Aspects related to inherent toxicity are mostly due to the elements contained with the QD core, such as cadmium and selenium, which exhibit significant toxicity to both cell cultures and live animals. Such studies have demonstrated toxicity at the supra-micromolar concentrations.
To summarize this section, we emphasize the following points: Despite the many advantages shown by QDs, there are concerns regarding their cytotoxicity.
It is difficult to provide a blanket evaluation of the toxicity of QDs because there are so many different categories according to their method of production, size, composition, charge, concentration, outer coating (capping material, functional groups), oxidative properties, photolytic conversion rate, and mechanical stability. All of these factors are determining factors in QD toxicity. Several studies have shown that QDs can cause damage to cells and produce significant DNA damage due to acute toxic effects. Evidence showed that if QDs were retained in cells or accumulated in the body for an extended period, their coatings might be degraded, yielding “naked” QDs can induce damage to the plasma membrane, mitochondrion, and nucleus, leading to cell death (Lovrić et al. 2005).
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1367826/ A Toxicologic Review of Quantum Dots: Toxicity Depends on Physicochemical and Environmental Factors - PMC (nih.gov)
Applications of Quantum Dots
Quantum dots are semiconductor nanocrystals (~ 2–100 nm) with unique optical and electrical properties (Bruchez et al. 1998; Dabbousi et al. 1997) currently applied in biomedical imaging and electronics industries. One of the more valuable properties of QDs is their fluorescence spectrum, which renders them optimal fluorophores for biomedical imaging (Alivisatos 2004; Chan et al. 2002). For instance, fluorescent QDs can be conjugated with bioactive moieties (e.g., antibodies, receptor ligands) to target specific biologic events and cellular structures, such as labeling neoplastic cells (Gao et al. 2004; Wu et al. 2003), peroxisomes (Colton et al. 2004), DNA (Dubertret et al. 2002), and cell membrane receptors (Beaurepaire et al. 2004; Lidke et al. 2004). Bioconjugated QDs are also being explored as tools for site-specific gene and drug delivery (Rudge et al. 2000; Scherer et al. 2001; Yu and Chow 2005) and are among the most promising candidates for a variety of information and visual technologies; they are currently used for the creation of advance flat-panel LED (light-emitting diode) displays and may be employed for ultrahigh-density data storage and quantum information processing (Wu et al. 2004).
Posted: Mar 14, 2016
'Sweet' quantum dots light the way for new HIV and Ebola treatment
(Nanowerk News) A research team led by the University of Leeds has observed for the first time how HIV and Ebola viruses attach to cells to spread infection. The findings, published today in the journal Angewandte Chemie ("Compact, Polyvalent Mannose Quantum Dots as Sensitive, Ratiometric FRET Probes for Multivalent Protein-Ligand Interactions"), offer a new way of treating such viruses: instead of destroying the pathogens, introduce a block on how they interact with cells.
Quantum dots are fluorescent crystals in which the color of the emitted light is dependent on the size of the crystal. (Image: Richard E. Cruise, University of Leeds)
https://www.sciencedirect.com/science/article/abs/pii/S1386947704002541Coherent optical control of semiconductor quantum dots for quantum information processing - ScienceDirect
https://outraged.substack.com/p/2-nobel-prizes-for-tagging-humans
ONLINE EXCLUSIVES
SICPA, UbiQD Develop QD-Based Anti-Counterfeit Security Inks
Quantum dot-based inks offer new possibilities for anti-counterfeiting and security applications.
Source: UbiQD - Q Ubi D
SICPA is the leading manufacturer of security inks in the world, with estimates placing SICPA’s security solutions appearing in up to 90% of the world’s currency, stamps and security documents such as passports. The company is also heavily involved in brand security, leveraging its experience to help combat counterfeiting.
https://currency-news.com/news/2023/sep/29/inx-and-sicpa-team-cbdc/ Currency News (currency-news.com)
https://www.ledgerinsights.com/cbdc-central-bank-sicpa-venture-inx/
SICPA plans to use its advanced security features in the CBDC joint venture.
“We believe that the unique form of CBDC we are working toward is an ecosystem and not only a tech solution,” said INX’s Deputy CEO and COO, Itai Avneri. “We harness the power of blockchain (trust, efficiency, cross-border, programmability, compliance, traceability and more) to cultivate a holistic solution that addresses the key requirements for CBDC, which include privacy-preserving, security, financial inclusion, resilience, and more.”
The CBDC offering will be based on blockchain and aims to “expand interoperability between different stakeholders across borders.”
Swiss-based SICPA is no stranger to blockchain and digital identity.
The U.S. Department of Homeland Security awarded a small project for decentralized identity back in 2019. The project’s aim was to ensure that digital credentials are at least as secure as physical credentials. In 2020, SICPA partnered with blockchain firm Guardtime for COVID-19 certificates.
Plus, it was an early investor in Swiss digital asset custody firm Metaco which boasts several banks as clients, including Citi and Standard Chartered.
THE WHOLE WORLD IS BEING TORTURED TO IMPLANT OR INSTILL THESE TOXIC QUANTUM DOTS INTO PEOPLE. THAT'S WHY THERE ARE SO MANY DEATHS, SO MANY ADVERSE EFFECTS, SO MUCH MENTAL SUFFERING.
IT'S TORTURE AND MURDER.
https://www.suggest.com/what-happened-to-chuck-norris-now/192306/
What Happened To Chuck Norris? Here’s What He’s Doing Now In 2023
The man, the myth, the legend: Chuck Norris transcended traditional celebrity status in the early 2000s and became an online legend.
Remember when you couldn’t go a day without hearing a Chuck Norris joke about his otherworldly strength and physical prowess? Those memes have died down in recent years, but now, claims of the actor’s death make the rounds on an annual basis.
Between the jokes and the hoaxes, we can’t help but wonder what Chuck Norris is doing these days. He was once one of Hollywood’s most recognizable action stars, but now he keeps a pretty low profile. We did some research to determine where Chuck Norris is now and if he has any big plans for the future.
Chuck Norris Stepped Away From Hollywood To Care For His Wife
In 2017, Norris’s wife, Gena, developed an enigmatic illness after a series of MRI scans. According to a report by the Mirror, Gena was given three gadolinium injections over the course of eight days in an attempt to help diagnostic imaging efforts. From there, she experienced joint pain, weakness, rib pain, and full-body tremors. She lost 15 pounds and had to be fed baby food because she was having a difficult time swallowing.
It was a medical mystery, but the Norris family chalked it up to gadolinium poisoning. Doctors disagreed. Gena finally found relief through a Nevada clinic, but her husband left Hollywood to care for her and raise awareness about gadolinium and its potential side effects. They also took the matter to court. However, the couple dropped their $10 million lawsuit in 2020.
https://www.mirror.co.uk/3am/celebrity-news/chuck-norris-reveals-gave-up-11479416
The couple maintain the injection has wrecked her health as a result.
They spoke to Good Health about her illness, with Gena saying:
"Within hours after the first jab I felt like my whole body was on fire — as if acid had been passed through it.
"The burning was isolated at first, but it just kept spreading."
She was then rushed to hospital six times over the coming weeks with excruciating rib pain, breathing difficulties, full-body tremors, muscle weakness, and joint pain.
After spending $2 million (£1.5 million) of their own money treating her illness, Chuck has left the movie business and is now devoting his life to helping Gena raise awareness for gadolinium poisoning.
He said: "I've given up my film career to concentrate on Gena, my whole life right now is about keeping her alive. I believe this issue is so important."
Now, as the 00s saying goes, we know "what Chuck Norris would do".
He said in an article on World Net Daily this week:
"The...years have been riddled with debilitating bouts of pain and anguish, as we have literally traveled the globe in pursuit of alternative medicine that may help her recover.
I heard a lecture by Dr. Dietrich Klinghardt that cilantro can detox gadolinium.
I'm sure that they tried a specific chelating agent called ZnDTPA to bind Gd, but afaik Gd is even harder to remove than Hg. After all these years I still haven't heard of any success story of getting rid from Gd. The Gd lobby is still strong and there's barely anything we can do about it. On a side note: I also had elevated levels of Gd in my body even though I've never received an MRI. My best guess is an accumulation of various sources including water, food and both MURDERNA shots (regret this every day).