NANOTECHNOLOGY - THE ELEPHANT IN THE ROOM

ALL THESE ADVERSE EFFECTS AND DEATHS - BUT WHY??????????????

What about NANOTECHNOLOGY in everything????

COULD THIS BE THE REASON????

COVID-19 linked to 40% increase in autoimmune disease risk in huge study

https://www.livescience.com/covid-19-linked-to-40-increase-in-autoimmune-disease-risk-in-huge-study

https://react19.org/science

https://twitter.com/DrJohnB2

AND SO ON AND SO FOR

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NANOTECHNOLOGY HAS BEEN USED IN LITERALLY EVERYTHING IN THIS "PANDEMIC"

CAN IT BE NANOTECHNOLOGY THAT CAN CAUSE THE ADVERSE EFFECTS AND DEATHS ASSOCIATED WITH COVID AND C-19 INJECTIONS????

https://web.archive.org/web/20220528084920/https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/adfm.202107826 Nanoscience versus Viruses: The SARS-CoV-2 Case First published: 13 December 2021

SO, WHAT ARE YOU BAFFLED BY?

https://europepmc.org/backend/ptpmcrender.fcgi?accid=PMC6774033&blobtype=pdf 2019

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This disruption is associated with many toxic effects within the coagulation system including disseminated intravascular coagulation (DIC)[16] which, depending whether it occurs acute or chronically, can induce abnormal hemorrhaging[17] or intravascular thrombosis[18] respectively. DIC occurs through depletion of coagulation factors and, if left untreated, can lead to organ failure and even death.[19]

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Alterations to the hemostatic balance can be induced directly or indirectly through various mechanisms by nanoparticles including platelet factor upregulation, platelet membrane damage, and endothelial cell interactions.

Activation of the complement system can result in inflammation,[40] immune cell activation,[41] and potentially even tumor growth.[42]

2.2.1. Liposomes

Liposomes consist of lipid bilayers with the ability to encapsulate drugs dissolved in solution enabling improved drug stability, reduced toxicity, and improved targeting in vivo. These nanoscale delivery systems have had great success in the area of oncology,[51] however many studies have reported concerns with liposome–opsonin interactions.

2.5.1. Immune Stimulation

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COVID??????????

Nanoparticle induced inflammation can also lead to liver and kidney tissue damage.[114] Moreover, inflammation in now a well-established hallmark of cancer but it is not know yet if anticancer drugs that indirectly induce proinflammatory effects have their efficacy reduced in vivo or even display tumor progressive effects.[115]

For example, Abraxane (albumin bound paclitaxel) has higher incidences of neuropathy than paclitaxel alone,[139] and Caelyx (liposomal doxorubicin) induces hand and foot syndrome at a higher rate than doxorubicin alone.[140]

3. Improving Immunotoxicity Assessment

3.1. Endotoxin Contamination Endotoxin is a component of gram-negative bacteria cell walls and a potent nanoparticle contaminant. Endotoxin poses a real treat to cancer nanomedicine development as low levels of the contaminant is known to drive immune stimulation, promote inflammation, tissue damage, and even septic shock.[142] Picogram levels of endotoxin have been shown to induce proinflammatory cytokine expression in vitro,[143] while human trials suggest a procoagulant [144] and immunoregulatory [145] profile.

Dobrovolskaia and McNeil reported in 2013 that more than 30% of nanomaterials fail early in preclinical studies due to endotoxin contamination based on nanomaterials evaluated by the US Nanoparticle Characterization Laboratory (USNCL).[149] Moreover, endotoxin contamination has been shown to vary between batches of the same nanomaterial produced from the same lab.[150] A lack of consistency and an absence of good manufacturing practice with nanomedicine synthesis could be detrimental for their translation.

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